WASHINGTON — Sixteen years after the Persian Gulf War ended, more than 1 in 4 of those who fought remain seriously ill with medical problems ranging from severe fatigue and joint pain to Lou Gehrig's disease, multiple sclerosis and brain cancer, the chairman of a congressional advisory committee testified yesterday.

But even as more is learned about what's now called Gulf War Veterans Illness, the Defense Department and the Department of Veterans Affairs remain in virtual denial about its causes and have been slow to offer treatment, said James Binns, head of the research advisory committee on the disease.

"This is a tragic record of failure, and the time lost can never be regained," Binns told the Senate Veterans' Affairs Committee. "This government manipulation of science and violation of law to devalue the health problems of ill veterans is something I would not have believed possible in this country until I took this job."

The hearing was called by Sen. Daniel Akaka, D-Hawai'i, chairman of the Senate committee.

APPROACH DEFENDED

Pentagon and VA officials defended their approach to studying and treating Gulf War Veterans Illness, saying they're taking it seriously, funding clinical and other research, and are committed to ensuring that Gulf War veterans receive needed care.

"Veterans who report health problems are definitely ill," said Michael Kilpatrick, the Defense Department's deputy director for force health protection and readiness programs.

Though the focus was on the earlier Gulf War, concerns hovered over the hearing that those now fighting in Iraq might face similar medical problems.

Fifteen percent to 20 percent of those who've fought in Iraq recently are returning with "ill-defined" medical symptoms, Kilpatrick said. He didn't elaborate.

MOTHER, KIDS AFFECTED

Among those testifying was Julie Mock, a 40-year-old mother of two from Seattle who served along the Iraq-Kuwait border with a medical unit. In early 1991, the alarms of chemical detectors went off repeatedly, she said.

"We ingested expired pyrostigmine bromide tablets; we wore gas masks with expired filters, inhaled dust and sand in the air that was thick with the black of burning oil," she said. "I experienced respiratory difficulties, my skin grew hot with red rashes and I began to suffer from debilitating headaches."

Four years ago, Mock was diagnosed with multiple sclerosis, a chronic disease that affects the central nervous system. Her voice choking with emotion, Mock told the committee that her oldest son has Tourette's syndrome and a handful of other neurological problems. Her youngest son has some of the same disorders.

Mock said she was convinced that the predeployment vaccines she received and chemical and other environmental exposures she underwent while serving in Iraq caused her health problems and those of her children. Her husband also served in the Gulf War but in a different area. He hasn't reported problems with his health.

"We know persons who deployed with us in theater who have not been healthy since their deployment, and we know that there are many who have deteriorated slowly over the years and who are now in crisis," she said.

Of the 700,000 or so U.S. troops who served in the Persian Gulf War, 175,000 to 200,000 are sick, Binns said.

Others who testified said that in addition to the predeployment vaccines, the health problems that Gulf War veterans experienced might have been caused by exposure to the depleted uranium used in munitions and armor, low-level nerve agents such as sarin that were released when a large weapons depot was destroyed, and smoke from more than 600 burning oil wells in Kuwait.

Pentagon and VA officials long have linked Gulf War Veterans Illness to battlefield stress and other related psychological disorders.

"That's garbage," Binns said. He said the Pentagon had cut important research programs associated with the illness.

The VA has conducted more than 330 projects associated with the health problems of Gulf War veterans. Because of "persistent concerns," the agency will launch a study next year of possible links between the veterans and brain cancer and multiple sclerosis, said Joel Kuppersmith, the VA's chief research and development officer.

"VA's commitment to funding clinical trials to identify new therapies for ill Gulf War veterans continues to this day," he said.

"We must all work together to make this a reality so that what happened to our troops in the first Persian Gulf War is not repeated," Akaka said.

The Associated Press contributed the Akaka quote to this story.